It is completelyabsorbed orally except when taken with a fattymeal, widely distributed into tissues andmetabolized extensively by CYP2C19, CYP3A4,CYP2C9. Using Xe-CT to measure CBF, Darby et al demonstrated dopamine-induced hypertension increased CBF in ischemic, noninfarcted territories without produc-ing an increase in mean global CBF (23) Using Xe-CT to measure CBF, Darby et al demonstrated dopamine-induced hypertension increased CBF in ischemic, noninfarcted territories without produc-ing an increase in mean global CBF (23).
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